Upcoming NGS Workshop

Upcoming NGS Workshop

Dear UKEMS members

The UKEMS in collaboration with Twinstrand Biosciences are hosting a Next Generation Sequencing Workshop on Thursday 12th May at 1 Wimpole Street, London.

Error-corrected next generation sequencing (ecNGS) is revolutionizing human cancer diagnostics, powering liquid biopsy assays that can screen for cancer in the cell-free DNA of a person’s blood. Remarkably, and for the first time ever, the most advanced human cancer diagnostic technology available is actively being developed into genetic toxicology assays for potential use in regulatory mutagenicity, carcinogenicity, off-target gene editing and insertional mutagenesis assessment. Using ecNGS, it is now possible to simply sequence DNA and read the mutations present, obviating the need for reporter-based model systems, and perhaps even animal models all together. Applications in cancer research and aetiology, DNA repair and genomic instability and human disease are also emerging.

The workshop aims to raise awareness and advance the science of ecNGS for research and regulatory applications in the UK.

The workshop includes the following sessions:

  • ecNGS: Current and emerging technologies: Jesse Salk (Twinstrand Bio), Inigo Martincorena (Sanger Inst.), Bob Young (GTTC-NGS).
  • ecNGS: Concepts and mutational signatures: Jill Kucab (Kings College London), Clint Valentine (Twinstrand Bio).
  • Mutagenesis, Carcinogenesis and Regulatory Testing: Carole Yauk (University of Ottawa), Patricia Escobar (Merck), Kristine Witt (NIEHS/DNTP, retired).
  • Skills for ecNGS: Simon Reed (Cardiff University), Anne Ashford (AstraZeneca).


The meeting is relevant for academic, regulatory and industry scientists with an interest in the development and application of ecNGS.

Registration for the one-day workshop is £25. All information for the workshop, including up-to-date programme and how to register can be found on the meeting website using the new link here.

Register now via the meeting website using the new link here.

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